| ROUND 1 | TEAM | ORIGINAL | PLAYER | DETAILS |
|---|
| 1 | - | Shane Wright | 1. Buffalo Sabres: Won the draft lottery to retain the 1st overall pick | |
| 2 | - | Simon Nemec | 2. Arizona Coyotes: Won the second draft lottery to move from 5th to 2nd overall | |
| 3 | - | Brad Lambert | 3. Columbus Blue Jackets | |
| 4 | - | Isaac Howard | 4. Anaheim Ducks | |
| 5 | - | Ivan Miroshnichenko | 5. Los Angeles Kings | |
| 6 | - | Logan Cooley | 6. Detroit Red Wings | |
| 7 | - | Jack Hughes | 7. New Jersey Devils | |
| 8 | - | Rutger McGroarty | 8. Nashville Predators | |
| 9 | David Jiricek | 9. San Jose Sharks | ||
| 10 | - | Danila Yurov | 10. Ottawa Senators | |
| 11 | - | Draft Pick Forfeited | ||
| 12 | Seamus Casey | 11. Columbus Blue Jackets (via Chicago Blackhawks) | ||
| 13 | - | Conor Geekie | 12. Seattle Kraken | |
| 14 | Juraj Slafkovsky | 13. Arizona Coyotes (via Montreal Canadiens) | ||
| 15 | Joakim Kemell | 14. NY Rangers | ||
| 16 | - | Frank Nazar | 15. Philadelphia Flyers | |
| 17 | - | Matt Savoie | 16. Vancouver Canucks | |
| 18 | - | Nosh Ostlund | 17. Buffalo Sabres (via Florida Panthers) | |
| 19 | - | Lian Bischel | 18. Dallas Stars | |
| 20 | Elias Salomonsson | 19. Calgary Flames | ||
| 21 | - | Maddox Fleming | 20. St. Louis Blues | |
| 22 | Ryan Chesley | 21. Pittsburgh Penguins | ||
| 23 | Antonin Verrault | 22. Edmonton Oilers | ||
| 24 | - | Ludwig Persson | 23. Toronto Maple Leafs | |
| 25 | Nathan Gaucher | 24. Minnesota Wild | ||
| 26 | Cruz Lucius | 25. Winnipeg Jets | ||
| 27 | Filip Mesar | 26. Washington Capitals | ||
| 28 | - | Ryan Greene | 27. Boston Bruins | |
| 29 | Justin Ct | Montreal Canadiens (via Carolina Hurricanes): This pick was transferred from Carolina to Montreal as compensation of the offer sheet that Jesperi Kotkaniemi signed with Carolina that was not matched by Montreal on September 4th, 2021 | ||
| 30 | - | Tristan Luneau | 29. NY Islanders | |
| 31 | - | Julian Lutz | 30. Vegas Golden Knights | |
| 32 | Charlie Leddy | 31. Tampa Bay Lightning |
| ROUND 2 | TEAM | ORIGINAL | PLAYER | DETAILS |
|---|
| 33 | - | Tyler Brennan | 32. Arizona Coyotes (via Colorado Avalanche) | |
| 34 | - | Denton Mateychuk | 33. Buffalo Sabres | |
| 35 | - | Jimmy James Snuggereud | 34. Columbus Blue Jackets | |
| 36 | Frank Nazar | 35. Anaheim Ducks | ||
| 37 | Cutter Gauthier | 36. Los Angeles Kings | ||
| 38 | Mattias Havelid | 37. Arizona Coyotes | ||
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